Fabp4 Polyclonal antibody

Fabp4 Polyclonal Antibody for ELISA
Cat No. 51035-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat and More (1)

应用

ELISA and More (2)

422/aP2, ALBP/Ap2, Ap2, Fabp4, Lbpl

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


产品信息

51035-1-AP targets Fabp4 in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 ELISA Application Description
文献引用应用WB, IF
经测试反应性 human, mouse, rat
文献引用反应性mouse, pig
免疫原 Fabp4 fusion protein Ag0712 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 fatty acid binding protein 4, adipocyte
别名 422/aP2, ALBP/Ap2, Ap2, Fabp4, Lbpl
计算分子量 15 kDa
观测分子量 15 kDa
GenBank蛋白编号BC054426
基因名称 Fabp4
Gene ID (NCBI) 11770
RRIDAB_670380
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP04117
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Aliquoting is unnecessary for -20oC storage.

背景介绍

Fatty acid binding protein (FABP) 4 is a member of the FABP family which abundantly expressed, fatty acid carrier proteins. FABPs are capable of binding a variety of hydrophobic molecules such as long-chain fatty acids and are important for their uptake and intracellular trafficking. It was first identified as an adipocyte-specific protein, important for the maintenance of lipid and glucose metabolism. It is also detected in macrophages, where it participates in regulating inflammation and cholesterol trafficking via NFκB and PPAR. In more recent studies, FABP4 has been found in a variety of endothelial cells, where it has been identified as a target of VEGF and a regulator of cell proliferation and possibly angiogenesis. Pathologically, FABP4 has been associated with the development of metabolic syndrome, diabetes and cancer and vulnerability of atherosclerotic plaques. FABP4 has been identified as a novel prognostic factor for both adverse cardiovascular events and breast cancer.

实验方案

Product Specific Protocols
WB protocol for Fabp4 antibody 51035-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseIF

Cell

Ciliary Hedgehog Signaling Restricts Injury-Induced Adipogenesis.

Authors - Daniel Kopinke
pigWB

J Anim Sci

Antimicrobial peptide KR-32 alleviates Escherichia coli K88-induced fatty acid malabsorption by improving expression of FATP4.

Authors - H Liu
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