验证数据展示
产品信息
24560-1-PBS targets FYTTD1 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag20051 Product name: Recombinant human FYTTD1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 68-128 aa of BC039734 Sequence: MRVRWGIQQNSGFGKTSLNRRGRVMPGKRRPNGVITGLAARKTTGIRKGISPMNRPPLSDK 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | forty-two-three domain containing 1 |
| 别名 | Forty-two-three domain-containing protein 1, Protein 40-2-3, UAP56-interacting factor, UIF |
| 计算分子量 | 318 aa, 36 kDa |
| 观测分子量 | 50 kDa |
| GenBank蛋白编号 | BC039734 |
| 基因名称 | FYTTD1 |
| Gene ID (NCBI) | 84248 |
| RRID | AB_2879609 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q96QD9 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
FYTTD1, also termed as UAP56 interacting factor or UIF, is a 318 amino acid protein, that belongs to the UIF family. FYTTD1 localizes to the nucleus and is required for mRNA export from the nucleus to the cytoplasm. Functioning as an adaptor, FYTTD1 utilizes the BAT1/DDX39-TAP pathway, which is essential for efficient mRNA export and nuclear pore delivery. FYTTD1 interacts with SSRP1, a protein that is necessary for its recruitment of mRNAs, in addition to a mutually exclusive interaction with BAT1/DDX39 and TAP. The molecular weight of post-translational modified FYTTD1 is observed to be 50 kDa.
