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验证数据展示

  • IHC staining of human pituitary using 67131-1-Ig (same clone as 67131-1-PBS)

    IHC staining of human pituitary using 67131-1-Ig (same clone as 67131-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pituitary tissue slide using 67131-1-Ig (FSH beta antibody) at dilution of 1:1000 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67131-1-PBS in a different storage buffer formulation.

  • IHC staining of human pituitary using 67131-1-Ig (same clone as 67131-1-PBS)

    IHC staining of human pituitary using 67131-1-Ig (same clone as 67131-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pituitary tissue slide using 67131-1-Ig (FSHB antibody) at dilution of 1:1000 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67131-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 67131-1-Ig (same clone as 67131-1-PBS)

    IF Staining of HepG2 using 67131-1-Ig (same clone as 67131-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using FSH beta antibody (67131-1-Ig, Clone: 1B10A11 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67131-1-PBS in a different storage buffer formulation.

FSH beta Monoclonal antibody, PBS Only

FSH beta Monoclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 67131-1-PBS

产品说明书

CloneNo. 1B10A11

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

IHC, IF/ICC, Indirect ELISA

别名

FSHB, 1B10A11, Follicle-stimulating hormone beta subunit, Follitropin beta chain, Follitropin subunit beta

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

67131-1-PBS targets FSH beta in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag13788

Product name: Recombinant human FSHB protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 19-129 aa of BC113488

Sequence: NSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKDPARPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPSYCSFGEMKE

种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 follicle stimulating hormone, beta polypeptide
别名 FSHB, 1B10A11, Follicle-stimulating hormone beta subunit, Follitropin beta chain, Follitropin subunit beta
计算分子量 129 aa, 15 kDa
GenBank蛋白编号BC113488
基因名称 FSHB
Gene ID (NCBI) 2488
RRIDAB_2882430
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP01225
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The FSHB gene encodes the beta subunit of follicle-stimulating hormone (FSH), particularly expressed in gonadotroph cells within the anterior pituitary gland and plays a critical role in the regulation of gonadal function, pubertal maturation and reproductive processes in mammals. The transcription of the FSHB gene is critical for the production of the FSH hormone(PMID:28281143). And FSH is required for ovarian folliculogenesis in females, in males it promotes spermatogenesis in conjunction with testosterone(PMID:11739331). Mutations in FSHB gene would result in infertility both in men and women (PMID: 23766128).

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