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FPR1 Polyclonal antibody, PBS Only

FPR1 Polyclonal Antibody for WB, ELISA
Cat No. 26164-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

fMet Leu Phe receptor, FMLP, fMLP receptor, formyl peptide receptor 1, FPR

缓冲液配方: 
偶联物:  Unconjugated
规格价格库存


产品信息

26164-1-PBS targets FPR1 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag23105

Product name: Recombinant human FPR1 protein

Source: e coli.-derived, PET30a

Tag: 6*His

Domain: 140-203 aa of BC005315

Sequence: SLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGI

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 formyl peptide receptor 1
别名 fMet Leu Phe receptor, FMLP, fMLP receptor, formyl peptide receptor 1, FPR
计算分子量 38 kDa
观测分子量45 kDa
GenBank蛋白编号BC005315
基因名称 FPR1
Gene ID (NCBI) 2357
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP21462
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FPR1 is a Gi-coupled innate immune GPCR that detects formylated peptides from bacteria and damaged mitochondria, initiating leukocyte chemotaxis and inflammatory activation. Predominantly expressed in neutrophils and monocytes, FPR1 functions as a frontline danger sensor in host defense. Dysregulated FPR1 signaling contributes to infectious susceptibility, acute inflammatory injury, and tumor-associated immune modulation, underscoring its importance in innate immunity and inflammatory disease.

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