- Featured Product
- KD/KO Validated
FOXO6 Polyclonal antibody
FOXO6 Polyclonal Antibody for IHC, IP, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse and More (1)
Applications
IHC, IP, WB, ELISA and More (4)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | C2C12 cells, mouse brain tissue, mouse lung tissue |
| Positive IP detected in | mouse brain tissue |
| Positive IHC detected in | mouse brain tissue, human gliomas tissue, human brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Immunohistochemistry (IHC) | IHC : 1:250-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
19122-1-AP targets FOXO6 in WB, IP, IF, IHC, CoIP, ChIP, ELISA, FC (Intra) applications and shows reactivity with human, mouse samples.
| Tested Applications | IHC, IP, WB, ELISA |
| Cited Applications | WB, IF, IHC, CoIP, ChIP, FC (Intra) |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse, pig |
| Immunogen | Peptide 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | forkhead box protein O6 |
| Synonyms | forkhead box protein O6, FOXO6 |
| Calculated Molecular Weight | 51 kDa |
| Observed Molecular Weight | 70 kDa |
| GenBank Accession Number | AI361654 |
| Gene Symbol | FOXO6 |
| Gene ID (NCBI) | 100132074 |
| RRID | AB_10597247 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | A8MYZ6 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
FOXO6 is a member of the murine forkhead family of transcription factors. These forkhead transcription factors may play a role in maintenance. FOXO6 mRNA is predominantly expressed in the developing brain, indicating that FOXO6 may play an important role in the nervous system. FOXO6 has a isoform of 70 kDa when modified after translation (PMID:23639108).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for FOXO6 antibody 19122-1-AP | Download protocol |
| IHC protocol for FOXO6 antibody 19122-1-AP | Download protocol |
| IP protocol for FOXO6 antibody 19122-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Aging Cell Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling | ||
Elife Inhibition of mutant EGFR in lung cancer cells triggers SOX2-FOXO6-dependent survival pathways.
| ||
RNA Biol Enterotoxigenic Escherichia coli infection promotes enteric defensin expression via FOXO6-METTL3-m6A-GPR161 signalling axis.
| ||
Oncotarget Involvement of the FOXO6 transcriptional factor in breast carcinogenesis.
| ||
Oncotarget Elevated FOXO6 expression correlates with progression and prognosis in gastric cancer. | ||
Mol Cell Biol Dormant Pluripotent Cells Emerge during Neural Differentiation of Embryonic Stem Cells in a FoxO3-dependent Manner. |
