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验证数据展示

  • WB analysis of HeLa using 60307-1-Ig (same clone as 60307-1-PBS)

    WB analysis of HeLa using 60307-1-Ig (same clone as 60307-1-PBS)

    WB result of FOLR1 antibody (60307-1-Ig, 1:4000) with si-Control and si-FOLR1 transfected HeLa cells.. This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • WB analysis of human milk using 60307-1-Ig (same clone as 60307-1-PBS)

    WB analysis of human milk using 60307-1-Ig (same clone as 60307-1-PBS)

    human milk were subjected to SDS PAGE followed by western blot with 60307-1-Ig (FOLR1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 60307-1-Ig (FOLR1 Antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    IHC staining of human kidney using 60307-1-Ig (same clone as 60307-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 60307-1-Ig (FOLR1 Antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 60307-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

FOLR1 Monoclonal antibody, PBS Only

FOLR1 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 60307-1-PBS

产品说明书

CloneNo. 2B4B7

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

2B4B7, Adult folate binding protein, Adult folate-binding protein, FBP, Folate receptor 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

60307-1-PBS targets FOLR1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag19959

Product name: Recombinant human FOLR1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 55-93 aa of BC002947

Sequence: EQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMA

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 folate receptor 1 (adult)
别名 2B4B7, Adult folate binding protein, Adult folate-binding protein, FBP, Folate receptor 1
计算分子量 257 aa, 30 kDa
观测分子量 36-38 kDa
GenBank蛋白编号BC002947
基因名称 FOLR1
Gene ID (NCBI) 2348
RRIDAB_2881421
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDP15328
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Folate receptor 1 (FOLR1), also known as folate receptor alpha or adult folate-binding protein (FBP), is a 38-kDa glycoprotein belonging to the folate receptor family (PMID:15094207; 23528302). The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung, kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer, non-small cell lung cancer, breast cancer, kidney cancer and high-grade osteosarcoma (PMID: 23528302; 23357463).