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验证数据展示

  • IP experiment of HEK-293 using 31283-1-AP (same clone as 31283-1-PBS)

    IP experiment of HEK-293 using 31283-1-AP (same clone as 31283-1-PBS)

    IP result of anti-FNIP2 (IP:31283-1-AP, 4ug; Detection:31283-1-AP 1:500) with HEK-293 cells lysate 1470 ug. This data was developed using the same antibody clone with 31283-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 31283-1-AP (same clone as 31283-1-PBS)

    IHC staining of mouse kidney using 31283-1-AP (same clone as 31283-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31283-1-AP (FNIP2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31283-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 31283-1-AP (same clone as 31283-1-PBS)

    IHC staining of mouse kidney using 31283-1-AP (same clone as 31283-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 31283-1-AP (FNIP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31283-1-PBS in a different storage buffer formulation.

FNIP2 Polyclonal antibody, PBS Only

FNIP2 Polyclonal Antibody for IHC, IP, Indirect ELISA
Cat No. 31283-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, IP, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

31283-1-PBS targets FNIP2 in IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag35014

Product name: Recombinant human FNIP2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 740-885 aa of BC166693

Sequence: ERVKACGPSLEASEAADVAQDPQVSRSPFKPGFQENVCCPQNRLSEGDEGESDKGFAEDRGSRNDMAADIAGQLSHAADLGTASHGAGGTGGRRLEATRGLYVKAAEGPVLEPVAPRCVQRGPGLVAGANIPCGDDNKKANFRTEG

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 folliculin interacting protein 2
别名
观测分子量125 kDa
GenBank蛋白编号BC166693
基因名称 FNIP2
Gene ID (NCBI) 57600
RRIDAB_3669929
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9P278
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Folliculin (FLCN)-interacting proteins 1 and 2 (FNIP1, FNIP2) are homologous binding partners of FLCN, a tumor suppressor for kidney cancer. FNIP2 was found to bind to the C terminus of FLCN and to AMPK, like FNIP1. FNIP2 competes with the activating co-chaperone AHSA1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PMID: 18403135).

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