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验证数据展示

  • IHC staining of human liver using 30977-1-AP (same clone as 30977-1-PBS)

    IHC staining of human liver using 30977-1-AP (same clone as 30977-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 30977-1-AP (FMO1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30977-1-PBS in a different storage buffer formulation.

  • IHC staining of human liver using 30977-1-AP (same clone as 30977-1-PBS)

    IHC staining of human liver using 30977-1-AP (same clone as 30977-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 30977-1-AP (FMO1 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30977-1-PBS in a different storage buffer formulation.

FMO1 Polyclonal antibody, PBS Only

FMO1 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 30977-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, Indirect ELISA

别名

Trimethylamine monooxygenase, Flavin-containing monooxygenase 1, Fetal hepatic flavin-containing monooxygenase 1, EC:1.14.13.148, Dimethylaniline monooxygenase [N-oxide-forming] 1

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

30977-1-PBS targets FMO1 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag34267

Product name: Recombinant human FMO1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 100-430 aa of NM_001282692

Sequence: LLKHIQFKTKVCSVTKCSDSAVSGQWEVVTMHEEKQESAIFDAVMVCTGFLTNPYLPLDSFPGINAFKGQYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQNMLRNSLPTPIVTWLMERKINNWLNHANYGLIPEDRTQLKEFVLNDELPGRIITGKVFIRPSIKEVKENSVIFNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLQKPTLAIIGLIKPLGSMIPTGETQARWAVRVLKGVNKLPPPSVMIEEINARKENKPSWFGLCYCKALQS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 flavin containing monooxygenase 1
别名 Trimethylamine monooxygenase, Flavin-containing monooxygenase 1, Fetal hepatic flavin-containing monooxygenase 1, EC:1.14.13.148, Dimethylaniline monooxygenase [N-oxide-forming] 1
计算分子量60 kDa
GenBank蛋白编号NM_001282692
基因名称 FMO1
Gene ID (NCBI) 2326
RRIDAB_3669802
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ01740
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Flavin-containing monooxygenase 1 (FMO1) belongs to the FMO family. FMO1 is an enzyme that catalyzes the oxygenation of a series of sulfur-containing and nitrogen-containing substrates, and thus is involved in a series of drugs and xenobiotics metabolism. FMO1 can regulate PPAR-α and mediate metabolic processes. FMO1 is expressed at relatively high levels in human fetal liver and also represents the major FMO enzyme in the adult human and rabbit intestine and kidney (PMID: 11809920, 30757917, 37553313). Human FMO1 has 2 isoforms with the molecular weights of 53 kDa and 60 kDa.

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