验证数据展示
产品信息
24845-1-PBS targets FIGLA in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 |
CatNo: Ag20392 Product name: Recombinant human FIGLA protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-219 aa of BC148798 Sequence: MDPAPGVLDPRAAPPALLGTPQAEVLEDVLREQFGPLPQLAAVCRLKRLPSGGYSSTENLQLVLERRRVANAKERERIKNLNRGFARLKALVPFLPQSRKPSKVDILKGATEYIQVLSDLLEGAKDSKKQDPDEQSYSNNSSESHTSSARQLSRNITQHISCAFGLKNEEEGPWADGGSGEPAHACRHSVMSTTEIISPTRSLDRFPEVELLSHRLPQV 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | folliculogenesis specific basic helix-loop-helix |
| 别名 | POF6, FIGalpha, Factor in the germline alpha, bHLHc8 |
| 计算分子量 | 219 aa, 24 kDa |
| 观测分子量 | 20 kDa |
| GenBank蛋白编号 | BC148798 |
| 基因名称 | FIGLA |
| Gene ID (NCBI) | 344018 |
| RRID | AB_3742126 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q6QHK4 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Folliculogenesis specific bHLH transcription factor(FIGLA) also known as POF6, is an oocyte-specific transcription factor expressed mainly in ovarian follicles and involved in regulating follicle formation and oocyte development. It regulates the expression of oocyte zona pellucida genes (such as Zp1, Zp2 and Zp3) by binding to the promoter regions of these genes (PMID: 15044608). Mutations in this gene cause premature ovarian failure type 6(PMID: 18499083).
