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验证数据展示

  • WB analysis using 30202-1-AP

    WB analysis using 30202-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 30202-1-AP (FGFR3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

FGFR3 Polyclonal antibody

FGFR3 Polyclonal Antibody for WB, ELISA
Cat No. 30202-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, ELISA

别名

ACH, CD333, CEK2, FGFR 3, HSFGFR3EX

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存

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经过测试的应用

Positive WB detected inmouse brain tissue, mouse testis tissue
Planning an IHC experiment? We recommend our IHCeasy FGFR3 Ready-To-Use IHC Kit. FGFR3 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

30202-1-AP targets FGFR3 in WB, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse
免疫原 fusion protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 fibroblast growth factor receptor 3
别名 ACH, CD333, CEK2, FGFR 3, HSFGFR3EX
计算分子量88kd
观测分子量115 kDa
基因名称 FGFR3
Gene ID (NCBI) 2261
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP22607
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Fibroblast growth factors (FGFs) are polypeptide growth factors involved in a variety of activities including mitogenesis, angiogenesis, and wound healing (PMID: 1847508). The human FGF receptor family, a subfamily of receptor tyrosine kinases (RTKs), comprises of four family members-FGFR1, FGFR2, FGFR3, and FGFR4 (PMID: 23900974). Each receptor contains an extracellular domain with either two or three immunoglobulin-like domains, a transmembrane domain, and a cytoplasmic tyrosine kinase domain. FGFR3 binds acidic and basic fibroblast GH and plays a role in bone development and maintenance. Mutations in the FGFR3 gene lead to craniosynostosis and multiple types of skeletal dysplasia. Due to frequent mutations in certain cancers, the FGFR3 gene has also been associated with tumor progression.

实验方案

Product Specific Protocols
WB protocol for FGFR3 antibody 30202-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols