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验证数据展示

  • WB analysis using 83296-4-RR (same clone as 83296-4-PBS)

    WB analysis using 83296-4-RR (same clone as 83296-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83296-4-RR (FGD6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83296-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83296-4-RR

    Affinity and Kinetic Characterization of 83296-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83296-4-RR against Human FGD6 were performed. The affinity constant is 10.7 nM.

FGD6 Recombinant monoclonal antibody, PBS Only

FGD6 Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 83296-4-PBS

产品说明书

CloneNo. 240260A6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

Zinc finger FYVE domain-containing protein 24, ZFYVE24, FYVE, RhoGEF and PH domain-containing protein 6, 240260A6

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

83296-4-PBS targets FGD6 in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag22211

Product name: Recombinant human FGD6 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 289-348 aa of BC013319

Sequence: ACSSNKYGLDYLKNQPARVCEHCFQELQKLDHQHSPRIGSPGNHKSPSSALSSVLHSIPS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 FYVE, RhoGEF and PH domain containing 6
别名 Zinc finger FYVE domain-containing protein 24, ZFYVE24, FYVE, RhoGEF and PH domain-containing protein 6, 240260A6
计算分子量 1430 aa, 161 kDa
GenBank蛋白编号BC013319
基因名称 FGD6
Gene ID (NCBI) 55785
RRIDAB_3670963
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ6ZV73
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FGD6, also known as ZFYVE24, is localized on the Homo sapiens chromosome 12q22 and consists of 1,400 amino acids. Previous studies have reported that variations in FGD6 increase individual susceptibility to polypoidal choroidal vasculopathy. It was also demonstrated that FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts by regulating the assembly of different actin-based protein networks and activating Cdc42 at different locations.

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