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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 85390-2-RR (same clone as 85390-2-PBS)

    WB analysis using 85390-2-RR (same clone as 85390-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85390-2-RR (FCER1G antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85390-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85390-2-RR

    Affinity and Kinetic Characterization of 85390-2-RR

    Biolayer interferometry (BLl) kinetic assays of 85390-2-RR against Human FCER1G were performed. The affinity constant is 1.16 nM.

FCER1G Recombinant antibody, PBS Only

FCER1G Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85390-2-PBS

产品说明书

CloneNo. 242829E3

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, pig

应用

WB, Indirect ELISA

别名

242829E3, Fc epsilon RI gamma, Fc receptor gamma-chain, Fc-epsilon RI-gamma, FceRI gamma

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

85390-2-PBS targets FCER1G in WB, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, pig
免疫原 FCER1G fusion protein Ag4442 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
别名 242829E3, Fc epsilon RI gamma, Fc receptor gamma-chain, Fc-epsilon RI-gamma, FceRI gamma
计算分子量 87 aa, 10 kDa
观测分子量10 kDa
GenBank蛋白编号BC033872
基因名称 FcRγ
Gene ID (NCBI) 2207
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP30273
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FCER1G (Fc receptor gamma-chain, FcRgamma), also known as Fc-epsilon RI-gamma, or IgE Fc receptor subunit gamma (FceRI gamma), is a component of the high-affinity immunoglobulin E (IgE) receptor (Fc epsilon RI) which is a tetrameric complex of one alpha subunit, one beta subunit, and two disulfide-linked gamma subunits (PMID: 2146219; 2531187). Fc epsilon RI is present exclusively on mast cells and basophils, mediating allergic inflammatory signaling (PMID: 17438574). FCER1G is widely expressed and contains an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors (PMID: 19098920).