FBXO32 Recombinant antibody
FBXO32 Recombinant Antibody for FC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
FC, ELISA
Conjugate
Unconjugated
CloneNo.
230243H7
验证数据展示
经过测试的应用
Positive FC detected in | U-251 cells |
Planning an IHC experiment? We recommend our IHCeasy FBXO32 Ready-To-Use IHC Kit. FBXO32 primary antibody included.
推荐稀释比
Application | Dilution |
---|---|
Flow Cytometry (FC) | FC : 0.25 ug per 10^6 cells in a 100 µl suspension |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
82941-1-RR targets FBXO32 in FC, ELISA applications and shows reactivity with Human samples.
Tested Applications | FC, ELISA |
Tested Reactivity | Human |
Immunogen | FBXO32 fusion protein Ag29394 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Full Name | F-box protein 32 |
Synonyms | Atrogin 1, F box only protein 32, F box protein 32, Fbx32, FBXO32, FLJ32424, MAFbx, Muscle atrophy F box protein |
Calculated Molecular Weight | 355 aa, 42 kDa |
GenBank Accession Number | BC024030 |
Gene Symbol | FBXO32 |
Gene ID (NCBI) | 114907 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | Q969P5 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
FBXO32 (F box only protein 32), also known as Atrogin 1 or MAFbx, is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif F-box. This protein is an E3 ubiquitin ligase that is markedly up-regulated in muscle atrophy. FBXO32 is thus a potential drug target for the treatment of muscle atrophy. Some data support that FBXO32 may play an important role in tumorigenesis. Recent study reveal that FBXO32 targets the oncogenic protein c-Myc for ubiquitination and degradation through the proteasome pathway.