FANCG Polyclonal antibody

FANCG Polyclonal Antibody for IF, IP, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IF, IP, WB,ELISA

Conjugate

Unconjugated

Cat No : 10215-1-AP

Print datasheet

Synonyms

DNA repair protein XRCC9, FAG, FANCG, Fanconi anemia group G protein, Protein FACG, XRCC9



经过测试的应用

Positive WB detected inJurkat cells, mouse testis tissue, K-562 cells, HeLa cells, mouse thymus tissue
Positive IP detected inmouse testis tissue
Positive IF detected inHeLa cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
Immunofluorescence (IF)IF : 1:10-1:100
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

10215-1-AP targets FANCG in WB, IP, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IF, IP, WB,ELISA
Cited Applications IF, WB
Tested Reactivity human, mouse, rat
Cited Reactivityhuman
Immunogen FANCG fusion protein Ag0249 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name Fanconi anemia, complementation group G
Synonyms DNA repair protein XRCC9, FAG, FANCG, Fanconi anemia group G protein, Protein FACG, XRCC9
Calculated Molecular Weight 69 kDa
Observed Molecular Weight 65-68 kDa
GenBank Accession NumberBC000032
Gene Symbol FANCG
Gene ID (NCBI) 2189
RRIDAB_2231541
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO15287
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

FANCG, also named as XRCC9, is a vDNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. It's a candidate tumor suppressor gene. FANCA and FANCG are critical for the localization of the FANC core complex. FANCA and FANCG form a stable complex with a molecular weight of ∼500 kDa that is predicted to be a heterotetramer (PMID: 32002546).

实验方案

Product Specific Protocols
WB protocol for FANCG antibody 10215-1-APDownload protocol
IF protocol for FANCG antibody 10215-1-APDownload protocol
IP protocol for FANCG antibody 10215-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Sci Adv

Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair

Authors - Dinh Duc Nguyen
humanIF

J Cancer

Significant value of XRCC2 and XRCC9 expression in the prognosis of human ovarian carcinoma.

Authors - Yi Liu
humanWB

Clin Transl Oncol

Therapeutic benefits of niraparib tosylate as radio sensitizer in esophageal squamous cell carcinoma: an in vivo and in vitro preclinical study.

Authors - Yuzhong Cui