验证数据展示
产品信息
33208-1-PBS targets FAM21A in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag36997 Product name: Recombinant human FAM21A protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1100-1341 aa of BC082258 Sequence: AAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | family with sequence similarity 21, member A |
| 别名 | FAM21B, WASH complex subunit 2A, WASHC2A |
| 观测分子量 | 170 kDa |
| GenBank蛋白编号 | BC082258 |
| 基因名称 | FAM21A |
| Gene ID (NCBI) | 387680 |
| RRID | AB_3742896 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q641Q2 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The FAM21A protein, full name Family with sequence similarity 21 member A, belongs to the FAM21 protein family. This protein is a core subunit of the WASH complex (Wiskott-Aldrich syndrome protein and SCAR homolog complex) and plays a critical role in endosomal sorting and membrane trafficking. Its primary function is to recruit the WASH complex to the endosomal membrane surface by binding to phospholipids (such as phosphatidylinositol 4-phosphate) and the VPS35 subunit of the Retromer complex, thereby anchoring the complex to the correct position on the endosomal membrane.
