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验证数据展示

  • WB analysis using 16251-1-AP (same clone as 16251-1-PBS)

    WB analysis using 16251-1-AP (same clone as 16251-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16251-1-AP (FAF2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16251-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 16251-1-AP (same clone as 16251-1-PBS)

    WB analysis of HeLa using 16251-1-AP (same clone as 16251-1-PBS)

    WB result of FAF2 antibody (16251-1-AP; 1:6000; incubated at room temperature for 1.5 hours) with sh-Control and sh-FAF2 transfected HeLa cells. This data was developed using the same antibody clone with 16251-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 16251-1-AP (same clone as 16251-1-PBS)

    IHC staining of human breast cancer using 16251-1-AP (same clone as 16251-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 16251-1-AP (FAF2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16251-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FAF2 antibody included
  • IHC staining of human breast cancer using 16251-1-AP (same clone as 16251-1-PBS)

    IHC staining of human breast cancer using 16251-1-AP (same clone as 16251-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 16251-1-AP (FAF2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16251-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with FAF2 antibody included
  • IP experiment of mouse brain using 16251-1-AP (same clone as 16251-1-PBS)

    IP experiment of mouse brain using 16251-1-AP (same clone as 16251-1-PBS)

    IP result of anti-FAF2 (IP:16251-1-AP, 3ug; Detection:16251-1-AP 1:1000) with mouse brain tissue lysate 5000ug. This data was developed using the same antibody clone with 16251-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

FAF2 Polyclonal antibody, PBS Only

FAF2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 16251-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IP, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy FAF2 Ready-To-Use IHC Kit. FAF2 primary antibody included.

产品信息

16251-1-PBS targets FAF2 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag9236

Product name: Recombinant human FAF2 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 97-445 aa of BC014001

Sequence: YLIMLPFRFTYYTILDIFRFALRFIRPDPRSRVTDPVGDIVSFMHSFEEKYGRAHPVFYQGTYSQALNDAKRELRFLLVYLHGDDHQDSDEFCRNTLCAPEVISLINTRMLFWACSTNKPEGYRVSQALRENTYPFLAMIMLKDRRMTVVGRLEGLIQPDDLINQLTFIMDANQTYLVSERLEREERNQTQVLRQQQDEAYLASLRADQEKERKKREERERKRRKEEEVQQQKLAEERRRQNLQEEKERKLECLPPEPSPDDPESVKIIFKLPNDSRVERRFHFSQSLTVIHDFLFSLKESPEKFQIEANFPRRVLPCIPSEEWPNPPTLQEAGLSHTEVLFVQDLTDE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 Fas associated factor family member 2
别名
计算分子量 445 aa, 53 kDa
观测分子量 53 kDa
GenBank蛋白编号BC014001
基因名称 FAF2
Gene ID (NCBI) 23197
RRIDAB_2262469
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ96CS3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Protein ETEA (FAF2, or UBXD8) is a homolog to Fas-associated factor 1 (FAF1), which is involved in Fas-mediated apoptosis. ETEA protein directly interacts with and negatively regulates neurofibromin. ETEA contains both UBA and UBX domains and overexpression of ETEA downregulates neurofibromin in human cells. It may play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. ETEA is highly expressed in peripheral blood of patients with atopic dermatitis (AD) compared to normal individuals, and may regulate the resistance to apoptosis that is observed in T cells and eosinophils of AD patients.

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