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验证数据展示

  • WB analysis using 25373-1-AP (same clone as 25373-1-PBS)

    WB analysis using 25373-1-AP (same clone as 25373-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25373-1-AP (Exportin 4 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse liver using 25373-1-AP (same clone as 25373-1-PBS)

    IHC staining of mouse liver using 25373-1-AP (same clone as 25373-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 25373-1-AP (Exportin 4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

  • WB analysis of HEK-293 using 25373-1-AP (same clone as 25373-1-PBS)

    WB analysis of HEK-293 using 25373-1-AP (same clone as 25373-1-PBS)

    WB result of Exportin 4 antibody (25373-1-AP; 1:600; incubated at room temperature for 1.5 hours) with sh-Control and sh-Exportin 4 transfected HEK-293 cells. This data was developed using the same antibody clone with 25373-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

Exportin 4 Polyclonal antibody, PBS Only

Exportin 4 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 25373-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

XPO4, Exp4, Exportin-4, KIAA1721

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

25373-1-PBS targets Exportin 4 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag21845

Product name: Recombinant human XPO4 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 776-1124 aa of BC113571

Sequence: QEITATLEALCGIAEATQIDNVAILFNFLMDFLTNCIGLMEVYKNTPETVNLIIEVFVEVAHKQICYLGESKAMNLYEACLTLLQVYSKNNLGRQRIDVTAEEEQYQDLLLIMELLTNLLSKEFIDFSDTDEVFRGHEPGQAANRSVSAADVVLYGVNLILPLMSQDLLKFPTLCNQYYKLITFICEIFPEKIPQLPEDLFKSLMYSLELGMTSMSSEVCQLCLEALTPLAEQCAKAQETDSPLFLATRHFLKLVFDMLVLQKHNTEMTTAAGEAFYTLVCLHQAEYSELVETLLSSQQDPVIYQRLADAFNKLTASSTPPTLDRKQKMAFLKSLEEFMANVGGLLCVK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 exportin 4
别名 XPO4, Exp4, Exportin-4, KIAA1721
计算分子量 1151 aa, 130 kDa
观测分子量127 kDa
GenBank蛋白编号BC113571
基因名称 Exportin 4/XPO4
Gene ID (NCBI) 64328
RRIDAB_3085791
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9C0E2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

exportin 4 (XPO4) maps to chromosome 13q and belongs to the importin β family which acts as a bidirectional nuclear transport receptor. Decreased XPO4 expression has been shown to associate with hepatocellular carcinoma. A genome-wide copy number variation (CNV) association study in a small cohort of Malaysian subjects identified a CNV in XPO4 to be correlated with the progression of metabolic (dysfunction) associated fatty liver disease (MAFLD). (PMID: 34388518)

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