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  • KD/KO Validated

ERCC6/CSB Polyclonal antibody

ERCC6/CSB Polyclonal Antibody for IP, WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

IP, WB, ELISA and More (1)

Conjugate

Unconjugated

Cat No : 24291-1-AP

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Synonyms

ARMD5, ATP dependent helicase ERCC6, CKN2, Cockayne syndrome protein CSB, COFS, COFS1, CSB, ERCC6, ERCC6/CSB, RAD26



经过测试的应用

Positive WB detected inDU 145 cells, HeLa cells, PC-3 cells
Positive IP detected inHeLa cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24291-1-AP targets ERCC6/CSB in WB, IP, IF, ELISA applications and shows reactivity with human samples.

Tested Applications IP, WB, ELISA
Cited ApplicationsWB, IF
Tested Reactivity human
Cited Reactivityhuman, mouse
Immunogen ERCC6/CSB fusion protein Ag18009 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name excision repair cross-complementing rodent repair deficiency, complementation group 6
Synonyms ARMD5, ATP dependent helicase ERCC6, CKN2, Cockayne syndrome protein CSB, COFS, COFS1, CSB, ERCC6, ERCC6/CSB, RAD26
Calculated Molecular Weight 1493 aa, 168 kDa
Observed Molecular Weight 170 kDa
GenBank Accession NumberBC127104
Gene Symbol ERCC6
Gene ID (NCBI) 2074
RRIDAB_2879476
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP0DP91
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

实验方案

Product Specific Protocols
WB protocol for ERCC6/CSB antibody 24291-1-APDownload protocol
IP protocol for ERCC6/CSB antibody 24291-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Int J Mol Sci

A Gene Expression Signature to Predict Nucleotide Excision Repair Defects and Novel Therapeutic Approaches.

Authors - Rongbin Wei
mouseWB,IF

Front Mol Biosci

Blockage of ERCC6 Alleviates Spinal Cord Injury Through Weakening Apoptosis, Inflammation, Senescence, and Oxidative Stress.

Authors - Peng Zou
  • KD Validated
humanWB

Life Sci Alliance

Elevated glucose increases genomic instability by inhibiting nucleotide excision repair.

Authors - Alexandra K Ciminera