ERCC5 Monoclonal antibody, PBS Only

ERCC5 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 67055-1-PBS

产品说明书

CloneNo. 1G2C9

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

WB, Indirect ELISA

COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

67055-1-PBS targets ERCC5 in WB, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human
免疫原 ERCC5 fusion protein Ag28561 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 excision repair cross-complementing rodent repair deficiency, complementation group 5
别名 COFS3, ERCC5, ERCM2, UVDR, XPG, XPGC
计算分子量 1186 aa, 133 kDa
观测分子量 200 kDa
GenBank蛋白编号BC031522
基因名称 ERCC5
Gene ID (NCBI) 2073
RRIDAB_2882366
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP28715
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The human genes correcting DNA repair defects are termed excision-repair cross-complementing or ERCC genes. The ERCC5 gene corrects the excision repair deficiency of Chinese hamster ovary cell line UV135 of complementation group 5. The human ERCC5 gene product is a structure-specific endonuclease required for making the 3-prime incision during DNA nucleotide excision-repair (NER). It also plays an important role in regulating DNA excision repair, removal of bulky lesions caused by environmental chemicals or UV light [PMID:22815677]. The calculated molecular weight of ERCC5 is 133 kDa, but the modified ERCC5 protein is about 200 kDa.

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