验证数据展示
产品信息
29180-1-PBS targets EPB41L5 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag30300 Product name: Recombinant human EPB41L5 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 349-445 aa of BC032822 Sequence: GKTEYQTTKTNKARRSTSFERRPSKRYSRRTLQMKACATKPEELSVHNNVSTQSNGSQQAWGMRSALPVSPSISSAPVPVEIENLPQSPGTDQHDRK 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | erythrocyte membrane protein band 4.1 like 5 |
| 别名 | |
| 观测分子量 | 58 kDa |
| GenBank蛋白编号 | BC032822 |
| 基因名称 | EPB41L5 |
| Gene ID (NCBI) | 57669 |
| RRID | AB_3669676 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9HCM4 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
EPB41L5, a member of the NBL4 subgroup of the band 4.1 superfamily, contains a FERM domain and plays an important role in regulating the connection between plasma membrane proteins and the cytoskeleton underneath the plasma membrane (PMID: 30082297). EPB41L5 is a mesenchymal-specific protein induced during EMT (epithelial-mesenchymal transition) that promotes the disruption of cell-cell adhesion kinetics (PMID: 34784520). EPB41L5 exists as four alternatively spliced isoforms encoded by a gene located on human chromosome 2q14.2.
