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验证数据展示

  • WB analysis of U2OS using 83275-2-RR (same clone as 83275-2-PBS)

    WB analysis of U2OS using 83275-2-RR (same clone as 83275-2-PBS)

    U2OS cells were subjected to SDS PAGE followed by western blot with 83275-2-RR (EPB41L3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83275-2-PBS in a different storage buffer formulation.

  • WB analysis of U2OS using 83275-2-RR (same clone as 83275-2-PBS)

    WB analysis of U2OS using 83275-2-RR (same clone as 83275-2-PBS)

    WB result of EPB41L3 antibody (83275-2-RR; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-EPB41L3 transfected U2OS cells. This data was developed using the same antibody clone with 83275-2-PBS in a different storage buffer formulation.

  • FC experiment of U2OS using 83275-2-RR (same clone as 83275-2-PBS)

    FC experiment of U2OS using 83275-2-RR (same clone as 83275-2-PBS)

    1x10^6 U2OS cells were intracellularly stained with 0.25 ug EPB41L3 Recombinant antibody (83275-2-RR, Clone:230501D7) and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2)(red), or 0.25 ug Control Antibody (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer. This data was developed using the same antibody clone with 83275-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83275-2-RR

    Affinity and Kinetic Characterization of 83275-2-RR

    Biolayer interferometry (BLl) kinetic assays of 83275-2-RR against Human EPB41L3 were performed. The affinity constant is below 1 pM.

  • Featured Product
  • KD/KO验证

EPB41L3 Recombinant monoclonal antibody, PBS Only

EPB41L3 Uni-rAb® Recombinant Antibody for WB, FC (Intra), Indirect ELISA
Cat No. 83275-2-PBS

产品说明书

CloneNo. 230501D7

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, FC (Intra), Indirect ELISA

别名

230501D7, 4.1B, Band 4.1-like protein 3, Band 4.1-like protein 3, N-terminally processed, DAL1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy EPB41L3 Ready-To-Use IHC Kit. EPB41L3 primary antibody included.

产品信息

83275-2-PBS targets EPB41L3 in WB, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, FC (Intra), Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag1089

Product name: Recombinant human EPB41L3 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 191-312 aa of BC008377

Sequence: MQCKVILLDGSEYTCDVEKRSRGQVLFDKVCEHLNLLEKDYFGLTYRDAENQKNWLDPAKEIKKQVRSGAWHFSFNVKFYPPDPAQLSEDITRYYLCLQLRDDIVSGRLPCSFVTLALLGS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 erythrocyte membrane protein band 4.1-like 3
别名 230501D7, 4.1B, Band 4.1-like protein 3, Band 4.1-like protein 3, N-terminally processed, DAL1
计算分子量 121 kDa
观测分子量120-130 kDa
GenBank蛋白编号BC008377
基因名称 EPB41L3
Gene ID (NCBI) 23136
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDQ9Y2J2
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

EPB41L3, also known as 4.1B and DAL1, belongs to the protein 4.1 family. It is a tumor suppressor that inhibits cell proliferation and promotes apoptosis. EPB41L3 modulates the activity of protein arginine N-methyltransferases, including PRMT3 and PRMT5 (PMID: 15334060, 15737618). DAL1 loss is an early event in meningioma tumorigenesis (PMID: 10888600).

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