验证数据展示
发表文章中的应用
| WB | See 1 publications below |
产品信息
19693-1-AP targets EIF2C4 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | eukaryotic translation initiation factor 2C, 4 |
| 别名 | AGO4, Argonaute4, eIF 2C 4, eIF2C 4, EIF2C4, hAgo4, KIAA1567, Protein argonaute 4 |
| 计算分子量 | 97 kDa |
| GenBank蛋白编号 | NM_017629 |
| 基因名称 | EIF2C4 |
| Gene ID (NCBI) | 192670 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9HCK5 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
EIF2C4, also named as AGO4 and KIAA1567, belongs to the argonaute family and Ago subfamily. It is required for RNA-mediated gene silencing (RNAi). EIF2C4 binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. EIF2C4 lacks endonuclease activity and does not appear to cleave target mRNAs. It is also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).