验证数据展示
经过测试的应用
| Positive WB detected in | L02 cells, PC-3 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
26495-1-AP targets EGR3 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | EGR3 fusion protein Ag24152 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | early growth response 3 |
| 别名 | early growth response 3, Early growth response protein 3, EGR 3, PILOT |
| 计算分子量 | 387 aa, 43 kDa |
| 观测分子量 | 43 kDa |
| GenBank蛋白编号 | BC104765 |
| 基因名称 | EGR3 |
| Gene ID (NCBI) | 1960 |
| RRID | AB_3669540 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q06889 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
The early growth response (Egr) family of zinc finger transcription factors regulates critical genetic programs in cellular growth, differentiation, and function. EGR3 (Early Growth Response 3; also known as PILOT) is a member of the early growth response (Egr) gene family of transcription factors. EGR3 regulates the expression of genes involved in inflammation, including genes encoding various secreted cytokines and protease inhibitors. EGR3 functions as a master regulator of genes differentially expressed in the brains of patients with neuropsychiatric illnesses ranging from schizophrenia and bipolar disorder to Alzheimer's disease.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for EGR3 antibody 26495-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |