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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 82818-2-RR (same clone as 82818-2-PBS)

    WB analysis using 82818-2-RR (same clone as 82818-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82818-2-RR (EDNRB antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82818-2-PBS in a different storage buffer formulation.

  • FC experiment of Raji using 82818-2-RR (same clone as 82818-2-PBS)

    FC experiment of Raji using 82818-2-RR (same clone as 82818-2-PBS)

    1x10^6 Raji cells were intracellularly stained with 0.25 ug EDNRB Recombinant antibody (82818-2-RR, Clone:1O2) and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2)(red), or 0.25 ug Isotype Control (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 82818-2-PBS in a different storage buffer formulation.

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EDNRB Recombinant monoclonal antibody, PBS Only

EDNRB Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 82818-2-PBS

产品说明书

CloneNo. 1O2

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

ET BR, ET B, endothelin receptor type B, Endothelin receptor non-selective type, Endothelin B receptor

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

82818-2-PBS targets EDNRB in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

fusion protein

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 endothelin receptor type B
别名 ET BR, ET B, endothelin receptor type B, Endothelin receptor non-selective type, Endothelin B receptor
计算分子量 50 kDa
观测分子量60 kDa
GenBank蛋白编号NM_000115
基因名称 EDNRB
Gene ID (NCBI) 1910
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP24530
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

EDNRB (endothelin receptor type B) is a G-protein coupled heptahelical endothelin-1 (EDN1) receptor. EDN1, a known mediator of human myometrial contraction in vitro, belongs to a family of three 21-amino acid isopeptides (PMID:18497345). EDNRB is a 442-residue protein expressed post-natally in many tissues, particularly in the myenteric plexus, mucosal layer, ganglia, and blood vessels of the submucosa of the colon (PMID:11434563). Moreover, Both the EDNRA and EDNRB are expressed in vessels and can be bound by EDN1, but while EDNRA mediates a constrictive effect, EDNRB is involved in vasorelaxation and functions as a clearance receptor that scavenges circulating EDN1 (PMID:30171849).