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验证数据展示

  • WB analysis of HEK-293 using 20964-1-AP (same clone as 20964-1-PBS)

    WB analysis of HEK-293 using 20964-1-AP (same clone as 20964-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 20964-1-AP (EDNRB antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20964-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse placenta using 20964-1-AP (same clone as 20964-1-PBS)

    WB analysis of mouse placenta using 20964-1-AP (same clone as 20964-1-PBS)

    mouse placenta tissue were subjected to SDS PAGE followed by western blot with 20964-1-AP (EDNRB antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20964-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 20964-1-AP (same clone as 20964-1-PBS)

    IHC staining of human placenta using 20964-1-AP (same clone as 20964-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 20964-1-AP (EDNRB Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 20964-1-PBS in a different storage buffer formulation.

  • IHC staining of human placenta using 20964-1-AP (same clone as 20964-1-PBS)

    IHC staining of human placenta using 20964-1-AP (same clone as 20964-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 20964-1-AP (EDNRB Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 20964-1-PBS in a different storage buffer formulation.

EDNRB Polyclonal antibody, PBS Only

EDNRB Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 20964-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

20964-1-PBS targets EDNRB in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 endothelin receptor type B
别名
计算分子量 50 kDa
观测分子量 53-60 kDa
GenBank蛋白编号NM_000115
基因名称 EDNRB
Gene ID (NCBI) 1910
RRIDAB_2878774
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP24530
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

EDNRB (endothelin receptor type B) is a G-protein coupled heptahelical endothelin-1 (EDN1) receptor. EDN1, a known mediator of human myometrial contraction in vitro, belongs to a family of three 21-amino acid isopeptides (PMID:18497345). EDNRB is a 442-residue protein expressed post-natally in many tissues, particularly in the myenteric plexus, mucosal layer, ganglia, and blood vessels of the submucosa of the colon (PMID:11434563). Moreover, Both the EDNRA and EDNRB are expressed in ships and can be bound by EDN1. Still, while EDNRA mediates a constrictive effect, EDNRB is involved in vasorelaxation and functions as a clearance receptor that scavenges circulating EDN1 (PMID:30171849).

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