Destrin Monoclonal antibody
Destrin Monoclonal Antibody for WB,ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, mouse, rat, pig and More (1)
Applications
WB,ELISA
Conjugate
Unconjugated
CloneNo.
1A12D9
验证数据展示
经过测试的应用
| Positive WB detected in | A549 cells, HeLa cells, human platelet, pig rectum, rat rectum, pig brain, rat brain, mouse brain |
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:3000-1:20000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 1 publications below |
产品信息
67657-1-Ig targets Destrin in WB, ELISA applications and shows reactivity with Human, mouse, rat, pig samples.
| Tested Applications | WB,ELISA |
| Cited Applications | WB |
| Tested Reactivity | Human, mouse, rat, pig |
| Cited Reactivity | human |
| Immunogen | Destrin fusion protein Ag1402 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | destrin (actin depolymerizing factor) |
| Synonyms | ACTDP, Actin depolymerizing factor, ADF, bA462D18.2, Destrin, DSN, DSTN |
| Calculated Molecular Weight | 19 kDa |
| Observed Molecular Weight | 18-19 kDa |
| GenBank Accession Number | BC009477 |
| Gene Symbol | DSTN |
| Gene ID (NCBI) | 11034 |
| RRID | AB_2918496 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P60981 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Destrin (also known as actin depolymerization factor, ADF) is an actin-binding protein contributing to cytoskeletal dynamics by promoting rapid actin filament disassembly. By regulating actin cytoskeletal reorganization it plays an important role in the formation of filopodia, which further promotes tumor cell invasion and metastasis. Destrin has been reported to be overexpressed in primary colon cancer.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for Destrin antibody 67657-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Nat Cell Biol Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis |