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验证数据展示

  • WB analysis of HEK-293 using 60239-1-Ig (same clone as 60239-1-PBS)

    WB analysis of HEK-293 using 60239-1-Ig (same clone as 60239-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 60239-1-Ig (Desmocollin 2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60239-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse heart using 60239-1-Ig (same clone as 60239-1-PBS)

    IF Staining of mouse heart using 60239-1-Ig (same clone as 60239-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse heart tissue using Desmocollin 2 antibody (60239-1-Ig, Clone: 1H8G1 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60239-1-PBS in a different storage buffer formulation.

  • IF Staining of rat heart using 60239-1-Ig (same clone as 60239-1-PBS)

    IF Staining of rat heart using 60239-1-Ig (same clone as 60239-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat heart tissue using Desmocollin 2 antibody (60239-1-Ig, Clone: 1H8G1 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60239-1-PBS in a different storage buffer formulation.

Desmocollin 2 Monoclonal antibody, PBS Only

Desmocollin 2 Monoclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 60239-1-PBS

产品说明书

CloneNo. 1H8G1

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse, rat

应用

WB, IF-P, Indirect ELISA

别名

DSC2, 1H8G1, ARVD11, Cadherin family member 2, CDHF2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy Desmocollin 2 Ready-To-Use IHC Kit. Desmocollin 2 primary antibody included.

产品信息

60239-1-PBS targets Desmocollin 2 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Desmocollin 2 fusion protein Ag5450 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 desmocollin 2
别名 DSC2, 1H8G1, ARVD11, Cadherin family member 2, CDHF2
计算分子量 100 kDa
观测分子量 110 kDa
GenBank蛋白编号BC063291
基因名称 Desmocollin 2
Gene ID (NCBI) 1824
RRIDAB_2881362
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ02487
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelia and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.