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验证数据展示

  • WB analysis using 16781-1-AP (same clone as 16781-1-PBS)

    WB analysis using 16781-1-AP (same clone as 16781-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16781-1-AP (DcR2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16781-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 16781-1-AP (same clone as 16781-1-PBS)

    IHC staining of human kidney using 16781-1-AP (same clone as 16781-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney using 16781-1-AP (DcR2 antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 16781-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 16781-1-AP (same clone as 16781-1-PBS)

    IHC staining of human kidney using 16781-1-AP (same clone as 16781-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney using 16781-1-AP (DcR2 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 16781-1-PBS in a different storage buffer formulation.

DcR2 Polyclonal antibody, PBS Only

DcR2 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 16781-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

CD264, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL R4

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

16781-1-PBS targets DcR2 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag10208

Product name: Recombinant human TRAILR4 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 230-386 aa of BC052270

Sequence: FSCRKKFISYLKGICSGGGGGPERVHRVLFRRRSCPSRVPGAEDNARNETLSNRYLQPTQVSEQEIQGQELAELTGVTVESPEEPQRLLEQAEAEGCQRRRLLVPVNDADSADISTLLDASATLEEGHAKETIQDQLVGSEKLFYEEDEAGSATSCL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
别名 CD264, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL R4
计算分子量 386 aa, 42 kDa
观测分子量 50-55 kDa
GenBank蛋白编号BC052270
基因名称 DcR2
Gene ID (NCBI) 8793
RRIDAB_2256181
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UBN6
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Decoy receptor 2 (DcR2) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It functions as a decoy receptor for TNF-related apoptosis-inducing ligand (TRAIL), thereby inhibiting TRAIL-mediated apoptosis (PMID: 15538968; 9537512). It has been considered a tentative marker of cellular senescence (PMID: 16079833; 22751116). Additionally, DCR2 has been implicated in the regulation of renal fibrosis and cell senescence, contributing to the pathogenesis of diabetic nephropathy (PMID: 35661704).

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