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验证数据展示

  • WB analysis using 86886-1-RR (same clone as 86886-1-PBS)

    WB analysis using 86886-1-RR (same clone as 86886-1-PBS)

    Human placenta tissue lysate was subjected to SDS PAGE followed by western blot with 86886-1-RR (DcR1/TNFRSF10C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86886-1-PBS in a different storage buffer formulation.

  • WB analysis of JAR using 86886-1-RR (same clone as 86886-1-PBS)

    WB analysis of JAR using 86886-1-RR (same clone as 86886-1-PBS)

    JAR cells lysate was subjected to SDS PAGE followed by western blot with 86886-1-RR (DcR1/TNFRSF10C antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86886-1-PBS in a different storage buffer formulation.

DcR1/TNFRSF10C Recombinant monoclonal antibody, PBS Only

DcR1/TNFRSF10C Uni-rAb® Recombinant Antibody for WB, Indirect ELISA
Cat No. 86886-1-PBS

产品说明书

CloneNo. 251096G6

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Indirect ELISA

别名

DcR1, Antagonist decoy receptor for TRAIL/Apo-2L, CD263, Decoy receptor 1, LIT

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

86886-1-PBS targets DcR1/TNFRSF10C in WB, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Eg4677

Product name: recombinant human TRAIL R3/TNFRSF10C protein

Source: mammalian cells-derived, V37

Tag: C-rFc

Domain: 26-235 aa of NM_003841.5

Sequence: ATTARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSRCPSGEVQVSNCTSWDDIQCVEEFGANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAEETMTTSPGTPAPAAEETMTTSPGTPAPAAEETMITSPGTP

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
别名 DcR1, Antagonist decoy receptor for TRAIL/Apo-2L, CD263, Decoy receptor 1, LIT
计算分子量27 kDa
观测分子量60-75 kDa
GenBank蛋白编号NM_003841.5
基因名称 DcR1
Gene ID (NCBI) 8794
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDO14798
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Decoy receptor 1 (DcR1), also known as TNFRSF10C, CD263, TRAIL-R3, or TRID, is a member of the TNF-receptor superfamily. DcR1 is a receptor for the cytotoxic ligand TRAIL. In contrast to DR4/TRAIL-R1 and DR5/TRAIL-R2, DcR1 is a glycosylphosphatidylinositol (GPI)-linked membrane molecule that lacks a cytoplasmic region, including the death domain (PMID: 9314565; 9242611). DcR1 is not capable of inducing apoptosis and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis (PMID: 9242610). The apparent molecular weight of DcR1 is larger than the calculated molecular weight of 27 kDa, suggesting the presence of extensive post-translational modifications and/or unusual structural motifs (PMID: 9373179).

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