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- KD/KO Validated
DZIP1 Polyclonal antibody
DZIP1 Polyclonal Antibody for IF/ICC, IP, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
IF/ICC, IP, WB, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive WB detected in | HEK-293 cells, human brain tissue, human testis tissue, mouse skeletal muscle tissue, PC-3 cells |
| Positive IP detected in | HEK-293 cells |
| Positive IF detected in | PC-3 cells |
Planning an IHC experiment? We recommend our IHCeasy DZIP1 Ready-To-Use IHC Kit. DZIP1 primary antibody included.
推荐稀释比
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
| Immunofluorescence (IF) | IF : 1:20-1:200 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
13779-1-AP targets DZIP1 in WB, IP, IF, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | IF/ICC, IP, WB, ELISA |
| Cited Applications | WB, IF |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Immunogen | DZIP1 fusion protein Ag4772 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | DAZ interacting protein 1 |
| Synonyms | DAZ interacting protein 1, DAZ interacting protein 1/2, DZIP, DZIP1, DZIP2, DZIPt1, KIAA0996, RP11 23E3.3, Zinc finger protein DZIP1 |
| Calculated Molecular Weight | 867 aa, 98 kDa |
| Observed Molecular Weight | 100-113 kDa |
| GenBank Accession Number | BC041804 |
| Gene Symbol | DZIP1 |
| Gene ID (NCBI) | 22873 |
| RRID | AB_2096927 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q86YF9 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
DZIP1, also named as DZIP, DZIP2 and KIAA0996, belongs to the DZIP C2H2-type zinc-finger protein family. DZIP1 has been reported to be associated with centrosomes and ciliogenesis in cells (PMID: 32051257). DZIP1 may participate in spermatogenesis via its interaction with DAZ1, and play a role in primary formation (PMID: 15081113, 19852954). DZIP1 has 3 isoforms with the molecular mass of 31, 97 and 99 kDa. It may be a potential therapeutic target of oral squamous carcinoma (PMID: 31450126).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for DZIP1 antibody 13779-1-AP | Download protocol |
| IF protocol for DZIP1 antibody 13779-1-AP | Download protocol |
| IP protocol for DZIP1 antibody 13779-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Nat Genet Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease. | ||
Dev Biol A function for the Joubert syndrome protein Arl13b in ciliary membrane extension and ciliary length regulation. | ||
Dev Dyn DZIP1 regulates mammalian cardiac valve development through a Cby1-β-catenin mechanism.
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