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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 85397-4-RR (same clone as 85397-4-PBS)

    WB analysis using 85397-4-RR (same clone as 85397-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85397-4-RR (KIAA0325 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85397-4-PBS in a different storage buffer formulation.

DYNC1H1 Recombinant antibody, PBS Only

DYNC1H1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85397-4-PBS

产品说明书

CloneNo. 242706B12

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, Indirect ELISA

别名

DYNC1H 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy DYNC1H1 Ready-To-Use IHC Kit. DYNC1H1 primary antibody included.

产品信息

85397-4-PBS targets DYNC1H1 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原 DYNC1H1 fusion protein Ag2999 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 dynein, cytoplasmic 1, heavy chain 1
别名 DYNC1H 1
计算分子量 4646 aa, 532 kDa
观测分子量532 kDa
GenBank蛋白编号BC021297
基因名称 DYNC1H1
Gene ID (NCBI) 1778
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ14204
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Dyneins are a group of microtubule-activated ATPases that convert chemical energy into mechanical energy. It can be divided into 2 large subgroups, namely, the axonemal and cytoplasmic dyneins. The conventional cytoplasmic dynein comprises 2 heavy chain polypeptides and several intermediate and light chains. DYNC1H1 is a cytoplasmic dynein and belongs to the dynein heavy chain family. It acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. DYNC1H1 has been implicated in the degeneration of dopaminergic neuron axons and motor neurons in PD patients.