• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis of human testis using 67226-1-Ig (same clone as 67226-1-PBS)

    WB analysis of human testis using 67226-1-Ig (same clone as 67226-1-PBS)

    human testis tissue were subjected to SDS PAGE followed by western blot with 67226-1-Ig (DUOX1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67226-1-PBS in a different storage buffer formulation.

  • WB analysis of human placenta using 67226-1-Ig (same clone as 67226-1-PBS)

    WB analysis of human placenta using 67226-1-Ig (same clone as 67226-1-PBS)

    human placenta tissue were subjected to SDS PAGE followed by western blot with 67226-1-Ig (DUOX1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67226-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse stomach using 67226-1-Ig (same clone as 67226-1-PBS)

    IF Staining of mouse stomach using 67226-1-Ig (same clone as 67226-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse stomach tissue using DUOX1 antibody (67226-1-Ig, Clone: 3B8D6 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 67226-1-PBS in a different storage buffer formulation.

  • IF Staining of rat lung using 67226-1-Ig (same clone as 67226-1-PBS)

    IF Staining of rat lung using 67226-1-Ig (same clone as 67226-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat lung tissue using DUOX1 antibody (67226-1-Ig, Clone: 3B8D6 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67226-1-PBS in a different storage buffer formulation.

DUOX1 Monoclonal antibody, PBS Only

DUOX1 Monoclonal Antibody for WB, IF-P, Indirect ELISA
Cat No. 67226-1-PBS

产品说明书

CloneNo. 3B8D6

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse, rat

应用

WB, IF-P, Indirect ELISA

别名

3B8D6, DUOX, DUOX 1, EC:1.11.1.-, Large NOX 1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

67226-1-PBS targets DUOX1 in WB, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag18154

Product name: Recombinant human DUOX1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 614-703 aa of BC114938

Sequence: WIVARLRMRNFKRLQGQDRQSIVSEKLVGGMEALEWQGHKEPCRPVLVYLQPGQIRVVDGRLTVLRTIQLQPPQKVNFVLSSNRGRRTLL

种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 dual oxidase 1
别名 3B8D6, DUOX, DUOX 1, EC:1.11.1.-, Large NOX 1
计算分子量 1551 aa, 177 kDa
观测分子量 190-200 kDa, 177 kDa, 138 kDa
GenBank蛋白编号BC114938
基因名称 DUOX1
Gene ID (NCBI) 53905
RRIDAB_2882515
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ9NRD9
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DUOX1 (dual oxidase 1) is a calciumactivated transmembrane protein member of the NOX family of NADPH oxidases principally located on the apical surface of airway and thyroid epithelia (PMID: 28982074, 15677770, 10806195). DUOX1 is a strong generator of hydrogen peroxide (H2O2), via intra-molecular dismutation of superoxide (PMID: 25586178). Epithelial DUOX1 appears to participate in additional host defense actions, such as mucociliary clearance, and may contribute to inflammatory responses and epithelial repair processes during exogenous stress (PMID: 19386603). DUOX1 has two isofroms with the calculated molecular mass of 177 and 138 kDa, and apparent molecular mass of 180-200 kDa due to the glycosylation (PMID: 17643428, 19144650).

||
New chat Able
正在加载，请稍候...