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验证数据展示

  • IF Staining of mouse embryo using 25222-1-AP (same clone as 25222-1-PBS)

    IF Staining of mouse embryo using 25222-1-AP (same clone as 25222-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse embryo tissue using 25222-1-AP (DTX4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 25222-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse kidney using 25222-1-AP (same clone as 25222-1-PBS)

    WB analysis of mouse kidney using 25222-1-AP (same clone as 25222-1-PBS)

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with 25222-1-AP (DTX4 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25222-1-PBS in a different storage buffer formulation.

  • IF Staining of HEK-293 using 25222-1-AP (same clone as 25222-1-PBS)

    IF Staining of HEK-293 using 25222-1-AP (same clone as 25222-1-PBS)

    Immunofluorescent analysis of HEK-293 cells using 25222-1-AP (DTX4 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 25222-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

DTX4 Polyclonal antibody, PBS Only

DTX4 Polyclonal Antibody for WB, IF/ICC, IF-P, Indirect ELISA
Cat No. 25222-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IF/ICC, IF-P, Indirect ELISA

别名

deltex homolog 4 (Drosophila), Deltex4, E3 ubiquitin-protein ligase DTX4, EC:2.3.2.27, KIAA0937

缓冲液配方:  PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

25222-1-PBS targets DTX4 in WB, IF/ICC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IF/ICC, IF-P, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag18415

Product name: Recombinant human DTX4 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 51-213 aa of BC119011

Sequence: LDLIYPMVTGTLPKAQSWPVSPGPATSPPMSPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPLDSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRLAIAQSRVLIASGVPTVPVK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 deltex homolog 4 (Drosophila)
别名 deltex homolog 4 (Drosophila), Deltex4, E3 ubiquitin-protein ligase DTX4, EC:2.3.2.27, KIAA0937
计算分子量 619 aa, 67 kDa
观测分子量 67-70 kDa
GenBank蛋白编号BC119011
基因名称 DTX4
Gene ID (NCBI) 23220
RRIDAB_2879970
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y2E6
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DTX4, also named as KIAA0937, RNF155, is a 619 amino acid protein, which belongs to the Deltex family. DTX4 as a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX4 functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.

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