• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis using 17934-1-AP (same clone as 17934-1-PBS)

    WB analysis using 17934-1-AP (same clone as 17934-1-PBS)

    Mouse brain lysates were subjected to SDS PAGE followed by western blot with 17934-1-AP (DRD1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17934-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse brain using 17934-1-AP (same clone as 17934-1-PBS)

    IF Staining of mouse brain using 17934-1-AP (same clone as 17934-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed frozen OCT-embedded mouse brain tissue using DRD1 antibody (17934-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 17934-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

DRD1 Polyclonal antibody, PBS Only

DRD1 Polyclonal Antibody for WB, IF-Fro, ELISA
Cat No. 17934-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF-Fro, ELISA

别名

D(1A) dopamine receptor, DADR, Dopamine D1 receptor, dopamine receptor D1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

17934-1-PBS targets DRD1 in WB, IF-Fro, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF-Fro, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag12366

Product name: Recombinant human DRD1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 338-446 aa of BC074978

Sequence: RKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 dopamine receptor D1
别名 D(1A) dopamine receptor, DADR, Dopamine D1 receptor, dopamine receptor D1
计算分子量 446 aa, 49 kDa
观测分子量 50-75 kDa
GenBank蛋白编号BC074978
基因名称 DRD1
Gene ID (NCBI) 1812
RRIDAB_10598308
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP21728
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Dopamine is a neurotransmitter that plays a crucial role in physical and mental health, such as cardiovascular, hormonal, renal, and central nervous systems (PMID: 29220802). Five subtypes of mammalian dopamine receptors are grouped into two classes, the D1- and D2-like classes. The D1-like class includes D1 and D5 receptors whereas the D2-like class includes D2, D3, D4 subtypes (PMID: 9457173). Dopamine receptor D1 (DRD1) is the most abundant form of dopamine receptor in the central nervous system. DRD1 stimulates adenylate cyclase, modulates D2 receptor activity, regulates neuron growth and differentiation, and mediates several behavioral responses (PMID: 1977312). DRD1 has a calculated molecular weight of 49 kDa, larger apparent molecular weight of 60-80 kDa may be due to glycosylation (PMID: 1281547; 23821371).

||
New chat Able
正在加载，请稍候...