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  • KD/KO Validated

DPEP1 Polyclonal antibody

DPEP1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, ELISA and More (2)

Conjugate

Unconjugated

Cat No : 12222-1-AP

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Synonyms

Dehydropeptidase I, Dipeptidase 1, dipeptidase 1 (renal), DPEP1, hRDP, MBD1, MDP, Microsomal dipeptidase, RDP, Renal dipeptidase



经过测试的应用

Positive WB detected inHepG2 cells, mouse liver tissue, HEK-293 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:5000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

12222-1-AP targets DPEP1 in WB, IHC, FC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA
Cited Applications FC, IHC, WB
Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, monkey
Immunogen DPEP1 fusion protein Ag2907 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name dipeptidase 1 (renal)
Synonyms Dehydropeptidase I, Dipeptidase 1, dipeptidase 1 (renal), DPEP1, hRDP, MBD1, MDP, Microsomal dipeptidase, RDP, Renal dipeptidase
Calculated Molecular Weight 411 aa, 46 kDa
Observed Molecular Weight 46 kDa
GenBank Accession NumberBC017023
Gene Symbol DPEP1
Gene ID (NCBI) 1800
RRIDAB_2877837
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP16444
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

DPEP1(Dipeptidase 1) is also named as MDP, RDP and belongs to the peptidase M19 family. It is a glycoprotein that plays an important role in the regulation of leukotriene activity. DPEP1 converts lekotriene D4 to leukotriene E4.

实验方案

Product Specific Protocols
WB protocol for DPEP1 antibody 12222-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouse,humanWB

Cell

Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver.

Authors - Saurav Roy Choudhury
  • KO Validated
humanWB,FC

Sci Adv

Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion.

Authors - Anne von Mässenhausen
  • KD Validated
humanIHC

Sci Adv

Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury.

Authors - Arthur Lau
monkey

J Clin Invest

Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.

Authors - Arthur Lau
mouseWB

Nat Commun

A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.

Authors - Yuting Guan
  • KO Validated