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DPEP1 Polyclonal antibody

DPEP1 Polyclonal Antibody for WB, ELISA
Cat No. 12222-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat and More (1)

应用

WB, ELISA

MBD1, hRDP, EC:3.5.2.6, EC:3.4.13.19, Dehydropeptidase-I

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格价格库存


经过测试的应用

Positive WB detected inHepG2 cells, mouse liver tissue, HEK-293 cells

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:5000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

12222-1-AP targets DPEP1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, ELISA Application Description
文献引用应用WB
经测试反应性 human, mouse, rat
文献引用反应性human, mouse, monkey
免疫原

CatNo: Ag2907

Product name: Recombinant human DPEP1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-385 aa of BC017023

Sequence: MWSGWWLWPLVAVCTADFFRDEAERIMRDSPVIDGHNDLPWQLLDMFNNRLQDERANLTTLAGTHTNIPKLRAGFVGGQFWSVYTPCDTQNKDAVRRTLEQMDVVHRMCRMYPETFLYVTSSAGIRQAFREGKVASLIGVEGGHSIDSSLGVLRALYQLGMRYLTLTHSCNTPWADNWLVDTGDSEPQSQGLSPFGQRVVKELNRLGVLIDLAHVSVATMKATLQLSRAPVIFSHSSAYSVCASRRNVPDDVLRLVKQTDSLVMVNFYNNYISCTNKANLSQVADHLDHIKEVAGARAVGFGGDFDGVPRVPEGLEDVSKYPDLIAELLRRNWTEAEVKGALADNLLRVFEAVEQASNLTQAPEEEPIPLDQLGGSCRTHYGYSS

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 dipeptidase 1 (renal)
别名 MBD1, hRDP, EC:3.5.2.6, EC:3.4.13.19, Dehydropeptidase-I
计算分子量 411 aa, 46 kDa
观测分子量 46 kDa
GenBank蛋白编号BC017023
基因名称 DPEP1
Gene ID (NCBI) 1800
RRIDAB_2877837
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP16444
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

DPEP1(Dipeptidase 1) is also named as MDP, RDP and belongs to the peptidase M19 family. It is a glycoprotein that plays an important role in the regulation of leukotriene activity. DPEP1 converts lekotriene D4 to leukotriene E4.

实验方案

Product Specific Protocols
WB protocol for DPEP1 antibody 12222-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouse,humanWB

Cell

Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver.

Authors - Saurav Roy Choudhury
  • KO Validated
humanWB,FC

Sci Adv

Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion.

Authors - Anne von Mässenhausen
  • KD Validated
humanIHC

Sci Adv

Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury.

Authors - Arthur Lau
monkey

J Clin Invest

Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury.

Authors - Arthur Lau
mouseWB

Nat Commun

A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis.

Authors - Yuting Guan
  • KO Validated
mouse,humanWB

Int Immunopharmacol

Dipeptidase 1 promotes ferroptosis in renal tubular epithelial cells in diabetic nephropathy via inhibition of the GSH/GPX4 axis

Authors - Yan Li
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