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验证数据展示

  • WB analysis using 17601-1-AP (same clone as 17601-1-PBS)

    WB analysis using 17601-1-AP (same clone as 17601-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17601-1-AP (DNALI1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17601-1-PBS in a different storage buffer formulation.

  • IP experiment of mouse testis using 17601-1-AP (same clone as 17601-1-PBS)

    IP experiment of mouse testis using 17601-1-AP (same clone as 17601-1-PBS)

    IP result of anti-DNALI1 (IP:17601-1-AP, 4ug; Detection:17601-1-AP 1:1000) with mouse testis tissue lysate 4000ug. This data was developed using the same antibody clone with 17601-1-PBS in a different storage buffer formulation.

  • KD/KO Validated

DNALI1 Polyclonal antibody, PBS Only

DNALI1 Polyclonal Antibody for WB, IP, ELISA
Cat No. 17601-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IP, ELISA

别名

hp28, P28

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

17601-1-PBS targets DNALI1 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IP, ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag11652

Product name: Recombinant human DNALI1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-258 aa of BC046117

Sequence: MIPPADSLLKYDTPVLVSRNTEKRSPKARLLKVSPQQPGPSGSAPQPPKTKLPSTPCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 dynein, axonemal, light intermediate chain 1
别名 hp28, P28
计算分子量 258 aa, 30 kDa
观测分子量 30-33 kDa
GenBank蛋白编号BC046117
基因名称 DNALI1
Gene ID (NCBI) 7802
RRIDAB_2095372
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDO14645
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DNALI1 belongs to the inner dynein arm light chain family and encodes a subunit of the light intermediate chain of inner dynein arms of the axoneme of sperm flagella (PMID: 36792588). DNALI1 promotes neurodegeneration after traumatic brain injury via inhibition of autophagosome-lysosome fusion (PMID: 38348540). Mutation in DNALI1 Causes Male Infertility with Severe Oligoasthenoteratozoospermia in Humans (PMID: 38212584).

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