验证数据展示
产品信息
15483-1-AP targets DIDO1 in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | DIDO1 fusion protein Ag7826 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | death inducer-obliterator 1 |
| 别名 | BYE1, C20orf158, DATF 1, DATF1, death inducer obliterator 1, DIDO1, DIDO2, DIDO3, DIO 1, DIO1, hDido1, KIAA0333 |
| 计算分子量 | 244 kDa |
| GenBank蛋白编号 | BC004237 |
| 基因名称 | DIDO1 |
| Gene ID (NCBI) | 11083 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9BTC0 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
DIDO1, also named as DATF-1, C20orf158, DATF1, KIAA0333 and DIO-1, is a putative transcription factor, weakly pro-apoptotic when overexpressed. It is a tumor suppressor. In mice, DIDO1 is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. The human DIDO1 is similar to the mouse gene and therefore is thought to be involved in apoptosis. The immunogen of this antibody is the N-terminal of DIDO1. This antibody can recognize all the isoform of DATF1 (DIDO1,DIDO2,DIDO3 and a).