DEFA6 Polyclonal antibody

DEFA6 Polyclonal Antibody for WB, IHC, ELISA
Cat No. 17923-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, ELISA and More (1)

DEF6, DEFA6, Defensin 6, Defensin, alpha 6, defensin, alpha 6, Paneth cell, HD 6

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected inCOLO 320 cells, mouse small intestine tissue
Positive IHC detected inhuman small intestine tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy DEFA6 Ready-To-Use IHC Kit. DEFA6 primary antibody included.

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IFSee 2 publications below

产品信息

17923-1-AP targets DEFA6 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, ELISA Application Description
文献引用应用IF
经测试反应性 human, mouse
文献引用反应性human
免疫原 DEFA6 fusion protein Ag12341 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 defensin, alpha 6, Paneth cell-specific
别名 DEF6, DEFA6, Defensin 6, Defensin, alpha 6, defensin, alpha 6, Paneth cell, HD 6
计算分子量 100 aa, 11 kDa
GenBank蛋白编号BC093951
基因名称 DEFA6
Gene ID (NCBI) 1671
RRIDAB_2878468
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ01524
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. DEFA6 is alpha 6 of Defensin. This protein is secret expression and can be cleaved in to the fragments with MW 4-6 kDa. It can be used as a maker of Paneth cell. DEFA6 has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. it may protect cells against infection with HIV-1.

实验方案

Product Specific Protocols
WB protocol for DEFA6 antibody 17923-1-APDownload protocol
IHC protocol for DEFA6 antibody 17923-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
HumanIF

J Clin Invest

Human intestinal bitter taste receptors regulate innate immune responses and metabolic regulators in obesity.

Authors - Kathrin I Liszt
humanIF

Mol Metab

Bitter-tasting drugs tune GDF15 and GLP-1 expression via bitter taste or motilin receptors in the intestine of patients with obesity

Authors - Qian Wang
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