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DEDD Polyclonal antibody

DEDD Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC,ELISA

Conjugate

Unconjugated

Cat No : 10816-1-AP

Print datasheet

Synonyms

CASP8IP1, DEDD, DEDD1, DEDPro1, DEFT, FLDED 1, FLDED1, KE05

验证数据展示

  • IHC staining of human prostate cancer using 10816-1-AP

    IHC staining of human prostate cancer using 10816-1-AP

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 10816-1-AP (DEDD antibody) at dilution of 1:50 (under 10x lens).

经过测试的应用

Positive IHC detected inhuman prostate cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

IHCSee 1 publications below

产品信息

10816-1-AP targets DEDD in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC,ELISA
Cited ApplicationsIHC
Tested Reactivity human
Cited Reactivityhuman
Immunogen DEDD fusion protein Ag1195 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name death effector domain containing
Synonyms CASP8IP1, DEDD, DEDD1, DEDPro1, DEFT, FLDED 1, FLDED1, KE05
Calculated Molecular Weight 37 kDa
GenBank Accession NumberBC013910
Gene Symbol DEDD
Gene ID (NCBI) 9191
RRIDAB_2091534
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDO75618
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

DEDD, a member of a family of death effector domain-containing proteins, plays crucial roles in mediating apoptosis, regulating cell cycle, and inhibiting cell mitosis. DEDD may be a novel tumor repressor, which impedes metastasis by reversing the epithelial-mesenchymal transition (EMT) process in breast and colon cancers (PMID: 24839027).

实验方案

Product Specific Protocols
IHC protocol for DEDD antibody 10816-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanIHC

Methods Mol Biol

Use of the Tumor Repressor DEDD as a Prognostic Marker of Cancer Metastasis.

Authors - Qi Lv
View Article