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验证数据展示

  • WB analysis using 84438-6-RR (same clone as 84438-6-PBS)

    WB analysis using 84438-6-RR (same clone as 84438-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84438-6-RR (DDR1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84438-6-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 84438-6-RR (same clone as 84438-6-PBS)

    IHC staining of mouse brain using 84438-6-RR (same clone as 84438-6-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 84438-6-RR (DDR1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84438-6-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with DDR1 antibody included

DDR1 Recombinant antibody, PBS Only

DDR1 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 84438-6-PBS

产品说明书

CloneNo. 241796D10

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, Indirect ELISA

别名

Cell adhesion kinase, CD167a, CD167 antigen-like family member A, CD167, CAK

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy DDR1 Ready-To-Use IHC Kit. DDR1 primary antibody included.

产品信息

84438-6-PBS targets DDR1 in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 FusionProtein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 discoidin domain receptor tyrosine kinase 1
别名 Cell adhesion kinase, CD167a, CD167 antigen-like family member A, CD167, CAK
计算分子量101kDa
观测分子量120 kDa
GenBank蛋白编号NM_001297654.2
基因名称 DDR1
Gene ID (NCBI) 780
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ08345-1
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

DDR1, or Discoidin Domain Receptor 1, is a member of the receptor tyrosine kinase (RTK) family, which plays a significant role in various cellular processes including cell proliferation, adhesion, migration, and extracellular matrix (ECM) remodeling. DDR1 is known for its unique discoidin domain that allows it to bind specifically to certain collagens, initiating downstream signaling pathways that can lead to cell transformation and tumor progression. Abnormal activation of DDR1 is closely associated with the development of various solid tumors, and it has been shown that DDR1 can prevent immune cells from infiltrating triple-negative breast cancer (TNBC) and eliminate tumor cells.