验证数据展示
经过测试的应用
| Positive WB detected in | mouse brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
28144-1-AP targets DCHS1 in WB, ELISA applications and shows reactivity with Human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | Human, mouse |
| 免疫原 |
CatNo: Ag27226 Product name: Recombinant human DCHS1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1517-1718 aa of NM_003737 Sequence: MPANASRRRAARVSARVFVTDENDNAPVFASPSRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLASGGDGHFRLHSSTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQVTYGGVSSESFSLDPDTGVLTTLRALDREEQEEIN 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | dachsous 1 (Drosophila) |
| 别名 | Cadherin 19, Cadherin 25, CDH19, CDH25, dachsous 1 (Drosophila), DCHS1, FIB1, Fibroblast cadherin 1, FLJ11790, KIAA1773, PCDH16, Protein dachsous homolog 1, Protocadherin 16 |
| 计算分子量 | 346 kDa |
| 观测分子量 | ~350 kDa |
| GenBank蛋白编号 | NM_003737 |
| 基因名称 | DCHS1 |
| Gene ID (NCBI) | 8642 |
| RRID | AB_3669648 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q96JQ0 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
DCHS1 is one of two known pathogenic genes associated with mitral valve prolapse (MVP) , a common cardiac valve disease (PMID: 33225636). Dchs1 and Fat4 function as a ligand-receptor pair during murine development and these genes are required in multiple organs (PMID: 21303848).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for DCHS1 antibody 28144-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
