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Cytochrome c Monoclonal antibody, PBS Only

Cytochrome c Monoclonal Antibody for WB,Indirect ELISA,IHC,IF,FC

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat

Applications

WB,Indirect ELISA,IHC,IF,FC

Conjugate

Unconjugated

CloneNo.

2D8D11

Cat No : 66264-1-PBS

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Synonyms

CYC, CYCS, Cytochrome c, cytochrome c, somatic, HCS, THC4



Planning an IHC experiment? We recommend our IHCeasy CYCS Ready-To-Use IHC Kit. CYCS primary antibody included.

产品信息

66264-1-PBS targets Cytochrome c in WB, IF, FC, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB,Indirect ELISA,IHC,IF,FC
Tested Reactivity human, mouse, rat
Immunogen Cytochrome c fusion protein Ag24349 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name cytochrome c, somatic
Synonyms CYC, CYCS, Cytochrome c, cytochrome c, somatic, HCS, THC4
Calculated Molecular Weight 12 kDa
Observed Molecular Weight 12-15 kDa
GenBank Accession NumberBC009578
Gene Symbol CYCS
Gene ID (NCBI) 54205
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP99999
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.