验证数据展示
产品信息
29306-1-PBS targets Cyclin G in Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag30937 Product name: Recombinant human CCNG1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 202-295 aa of BC007093 Sequence: VLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTFWQELVSKCLTEYSSNECSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | cyclin G1 |
| 别名 | |
| 计算分子量 | 34 kDa |
| 观测分子量 | 34 kDa |
| GenBank蛋白编号 | BC007093 |
| 基因名称 | Cyclin G |
| Gene ID (NCBI) | 900 |
| RRID | AB_3086111 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P51959 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Cyclin G is also named as CCNG, CYCG1 and CCNG1, and and belongs to the cyclin family. Cyclin G may play a role in growth regulation. Cyclin G is associated with G2/M phase arrest in response to DNA damage. And it may be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation, and levels of Cyclin G are increased after induction of p53 by DNA damage (PMID:12015958). Cyclin G is high levels in skeletal muscle, ovary, kidney and colon. Cyclin G is very low levels in normal cells during G1 phase, which increase as cells enter the S phase and stay high throughout the S and G2/M phases. In breast cancer cells, consistent high levels of Cyclin G are found throughout the cell cycle (PMID:11063931).
