验证数据展示
产品信息
87436-1-PBS targets Ccr10 in WB, Indirect ELISA applications and shows reactivity with mouse samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | mouse |
| 免疫原 |
Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | chemokine (C-C motif) receptor 10 |
| 别名 | C-C chemokine receptor type 10, C-C CKR-10, CC-CKR-10, CCR-10, Chemokine C-C receptor 9 |
| 观测分子量 | 35 kDa |
| GenBank蛋白编号 | BC117043 |
| 基因名称 | Ccr10 |
| Gene ID (NCBI) | 12777 |
| RRID | AB_3745545 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q9JL21 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Mouse Ccr10 is a Gi-coupled chemokine receptor that governs immune cell homing to skin and mucosal epithelia through recognition of Ccl27 and Ccl28. By directing T cells and IgA-secreting plasma cells to barrier tissues, Ccr10 plays a central role in cutaneous and mucosal immune surveillance. Genetic and functional studies in mice highlight Ccr10 as a key regulator of epithelial immunity and inflammatory balance.
