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Host
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Species Reactivity
0
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0
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0
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0
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验证数据展示

  • WB analysis using 85116-4-RR (same clone as 85116-4-PBS)

    WB analysis using 85116-4-RR (same clone as 85116-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85116-4-RR (CNTNAP2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85116-4-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 85116-4-RR (same clone as 85116-4-PBS)

    IHC staining of rat brain using 85116-4-RR (same clone as 85116-4-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 85116-4-RR (Caspr2/CNTNAP2 antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85116-4-PBS in a different storage buffer formulation.

  • IHC staining of rat brain using 85116-4-RR (same clone as 85116-4-PBS)

    IHC staining of rat brain using 85116-4-RR (same clone as 85116-4-PBS)

    Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 85116-4-RR (Caspr2/CNTNAP2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85116-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 85116-4-RR

    Affinity and Kinetic Characterization of 85116-4-RR

    Biolayer interferometry (BLl) kinetic assays of 85116-4-RR against Human Caspr2/CNTNAP2 were performed. The affinity constant is below 1 pM.

Caspr2/CNTNAP2 Recombinant antibody, PBS Only

Caspr2/CNTNAP2 Uni-rAbTM Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 85116-4-PBS

产品说明书

CloneNo. 242391A9

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

CNTNAP2, 242391A9, CASPR2, Contactin-associated protein-like 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

85116-4-PBS targets Caspr2/CNTNAP2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Caspr2/CNTNAP2 fusion protein Ag22844 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 contactin associated protein-like 2
别名 CNTNAP2, 242391A9, CASPR2, Contactin-associated protein-like 2
计算分子量 1331 aa, 148 kDa
观测分子量148 kDa
GenBank蛋白编号BC113373
基因名称 Grancalcin
Gene ID (NCBI) 26047
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9UHC6
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Caspr2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development.