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验证数据展示

  • WB analysis using 85717-1-RR (same clone as 85717-1-PBS)

    WB analysis using 85717-1-RR (same clone as 85717-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85717-1-RR (CYP2C8 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85717-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse liver using 85717-1-RR (same clone as 85717-1-PBS)

    IHC staining of mouse liver using 85717-1-RR (same clone as 85717-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 85717-1-RR (CYP2C8 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85717-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse liver using 85717-1-RR (same clone as 85717-1-PBS)

    IHC staining of mouse liver using 85717-1-RR (same clone as 85717-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 85717-1-RR (CYP2C8 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 85717-1-PBS in a different storage buffer formulation.

CYP2C8 Recombinant monoclonal antibody, PBS Only

CYP2C8 Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 85717-1-PBS

产品说明书

CloneNo. 242948A3

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

CP2C8, 242948A3, CPC8, CYP2C8/9/18/19, CYPIIC8

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

85717-1-PBS targets CYP2C8 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag9898

Product name: Recombinant human CYP2C8 protein

Source: e coli.-derived, T-HIS

Tag: 6*His

Domain: 142-490 aa of BC020596

Sequence: EDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 cytochrome P450, family 2, subfamily C, polypeptide 8
别名 CP2C8, 242948A3, CPC8, CYP2C8/9/18/19, CYPIIC8
计算分子量 490 aa, 56 kDa
观测分子量 50 kDa
GenBank蛋白编号BC020596
基因名称 CYP2C8
Gene ID (NCBI) 1558
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP10632
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CYP2C8(Cytochrome P450 2C8) is also named as CYPIIC8, cytochrome P450 IIC2, cytochrome P450 MP-12, cytochrome P450 MP-20, cytochrome P450 form 1 and S-mephenytoin 4-hydroxylase. It belongs to the cytochrome P450 family. It is a monooxygenase involved in an NADPH-dependent electron transport pathway and a hepatic drug-metabolizing enzymes that oxidizes therapeutic drugs such as cerivastatin and endobiotics such as retinoic acid and arachidonic acid. It has 2 isoforms produced by alternative splicing.

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