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验证数据展示

  • WB analysis of SKOV-3 using 83930-1-RR (same clone as 83930-1-PBS)

    WB analysis of SKOV-3 using 83930-1-RR (same clone as 83930-1-PBS)

    SKOV-3 cells were subjected to SDS PAGE followed by western blot with 83930-1-RR (CYP11B2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83930-1-PBS in a different storage buffer formulation.

CYP11B2 Recombinant antibody, PBS Only

CYP11B2 Recombinant Antibody for WB, ELISA
Cat No. 83930-1-PBS

产品说明书

CloneNo. 240811E7

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, ELISA

别名

240811E7, ALDOS, Aldosterone-synthesizing enzyme, Corticosterone 18-monooxygenase, CYP11B2, CPN2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

83930-1-PBS targets CYP11B2 in WB, ELISA applications and shows reactivity with human samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 cytochrome P450, family 11, subfamily B, polypeptide 2
别名 240811E7, ALDOS, Aldosterone-synthesizing enzyme, Corticosterone 18-monooxygenase, CYP11B2, CPN2
计算分子量 58 kDa
观测分子量 58-60 kDa
GenBank蛋白编号NM_000498
基因名称 CYP11B2
Gene ID (NCBI) 1585
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purfication
UNIPROT IDP19099
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CYP11B2 (Cytochrome P450 11B2), also known as aldosterone synthase, is a member of the cytochrome P450 superfamily of enzymes. CYP11B2 can only catalyze 11-deoxycorticosterone oxidation to produce corticosterone and further hydroxylation to ALD. CYP11B2 is an enzyme required for cortisol biosynthesis and is specifically expressed in aldosterone-producing tissue of the adrenal cortex and is overexpressed in aldosterone-producing adenomas (APA).