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验证数据展示

  • IHC staining of human adrenal gland using 20968-1-AP (same clone as 20968-1-PBS)

    IHC staining of human adrenal gland using 20968-1-AP (same clone as 20968-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human adrenal gland tissue slide using 20968-1-AP (CYP11B2 antibody) at dilution of 1:100 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.

  • IHC staining of human adrenal gland using 20968-1-AP (same clone as 20968-1-PBS)

    IHC staining of human adrenal gland using 20968-1-AP (same clone as 20968-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human adrenal gland tissue slide using 20968-1-AP (CYP11B2 antibody) at dilution of 1:100 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.

  • WB analysis of SKOV-3 using 20968-1-AP (same clone as 20968-1-PBS)

    WB analysis of SKOV-3 using 20968-1-AP (same clone as 20968-1-PBS)

    SKOV-3 cells were subjected to SDS PAGE followed by western blot with 20968-1-AP (CYP11B2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.

  • IF Staining of SKOV-3 using 20968-1-AP (same clone as 20968-1-PBS)

    IF Staining of SKOV-3 using 20968-1-AP (same clone as 20968-1-PBS)

    Immunofluorescent analysis of SKOV-3 cells using 20968-1-AP (CYP11B2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 20968-1-PBS in a different storage buffer formulation.

CYP11B2 Polyclonal antibody, PBS Only

CYP11B2 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 20968-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, pig

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

20968-1-PBS targets CYP11B2 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, pig
免疫原

Peptide

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 cytochrome P450, family 11, subfamily B, polypeptide 2
别名
计算分子量 58 kDa
观测分子量 48-50 kDa
GenBank蛋白编号NM_000498
基因名称 CYP11B2
Gene ID (NCBI) 1585
RRIDAB_2878777
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP19099
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CYP11B2 (Cytochrome P450 11B2), also known as aldosterone synthase, is a member of the cytochrome P450 superfamily of enzymes. CYP11B2 can only catalyze 11-deoxycorticosterone oxidation to produce corticosterone and further hydroxylation to ALD. CYP11B2 is an enzyme required for cortisol biosynthesis and is specifically expressed in aldosterone-producing tissue of the adrenal cortex and is overexpressed in aldosterone-producing adenomas (APA).

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