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验证数据展示

  • WB analysis of L02 using 20634-1-AP (same clone as 20634-1-PBS)

    WB analysis of L02 using 20634-1-AP (same clone as 20634-1-PBS)

    L02 cells were subjected to SDS PAGE followed by western blot with 20634-1-AP (CXCR2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20634-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 20634-1-AP (same clone as 20634-1-PBS)

    IHC staining of human tonsillitis using 20634-1-AP (same clone as 20634-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 20634-1-AP (CXCR2 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20634-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 20634-1-AP (same clone as 20634-1-PBS)

    IHC staining of human tonsillitis using 20634-1-AP (same clone as 20634-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 20634-1-AP (CXCR2 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20634-1-PBS in a different storage buffer formulation.

  • IP experiment of HepG2 using 20634-1-AP (same clone as 20634-1-PBS)

    IP experiment of HepG2 using 20634-1-AP (same clone as 20634-1-PBS)

    IP result of anti-CXCR2 (IP:20634-1-AP, 4ug; Detection:20634-1-AP 1:1000) with HepG2 cells lysate 3200ug. This data was developed using the same antibody clone with 20634-1-PBS in a different storage buffer formulation.

  • IF Staining of mouse liver using 20634-1-AP (same clone as 20634-1-PBS)

    IF Staining of mouse liver using 20634-1-AP (same clone as 20634-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse liver tissue using CXCR2 antibody (20634-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20634-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 20634-1-AP (same clone as 20634-1-PBS)

    IF Staining of HepG2 using 20634-1-AP (same clone as 20634-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using CXCR2 antibody (20634-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 20634-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

CXCR2 Polyclonal antibody, PBS Only

CXCR2 Polyclonal Antibody for WB, IHC, IF-P, IP, ELISA
Cat No. 20634-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, IF-P, IP, ELISA

别名

IL8RB, CD182, CDw128b, CMKAR2, C-X-C chemokine receptor type 2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

20634-1-PBS targets CXCR2 in WB, IHC, IF-P, IP, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, IF-P, IP, ELISA Application Description
经测试反应性 human
免疫原 CXCR2 fusion protein Ag14670 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 interleukin 8 receptor, beta
别名 IL8RB, CD182, CDw128b, CMKAR2, C-X-C chemokine receptor type 2
计算分子量 360 aa, 41 kDa
观测分子量 45-50 kDa
GenBank蛋白编号BC037961
基因名称 IL8RB
Gene ID (NCBI) 3579
RRIDAB_10693624
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP25025
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IL8RB, also named as CXCR2, GRO/MGSA receptor, IL-8 receptor type 2, CDw128b, and CD182, belongs to the G-protein coupled receptor 1 family. It is a receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. The binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. It binds to IL-8 with high affinity. IL8RB also binds with high affinity to CXCL3, GRO/MGSA, and NAP-2.