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Host
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Species Reactivity
0
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0
Conjugate
0
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Compatible Species
0
Conjugate
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验证数据展示

  • WB analysis using 86186-1-RR (same clone as 86186-1-PBS)

    WB analysis using 86186-1-RR (same clone as 86186-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86186-1-RR (CXADR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86186-1-PBS in a different storage buffer formulation.

  • WB analysis using 86186-1-RR (same clone as 86186-1-PBS)

    WB analysis using 86186-1-RR (same clone as 86186-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86186-1-RR (CXADR antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86186-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse heart using 86186-1-RR (same clone as 86186-1-PBS)

    IHC staining of mouse heart using 86186-1-RR (same clone as 86186-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 86186-1-RR (CXADR antibody) at dilution of 1:800 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 86186-1-PBS in a different storage buffer formulation.

  • IHC staining of rat heart using 86186-1-RR (same clone as 86186-1-PBS)

    IHC staining of rat heart using 86186-1-RR (same clone as 86186-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat heart tissue slide using 86186-1-RR (CXADR antibody) at dilution of 1:800 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 86186-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86186-1-RR

    Affinity and Kinetic Characterization of 86186-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86186-1-RR against Human CXADR were performed. The affinity constant is 96.1 pM.

    {{ptg:ProductFeaturesInfo}}

CXADR Recombinant monoclonal antibody, PBS Only

CXADR Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 86186-1-PBS

产品说明书

CloneNo. 250811C8

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

CAR, Coxsackievirus B-adenovirus receptor, CVB3 binding protein, CVB3-binding protein, HCAR

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

86186-1-PBS targets CXADR in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag34346

Product name: Recombinant human CXADR protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-365 aa of BC003684

Sequence: MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV*

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 coxsackie virus and adenovirus receptor
别名 CAR, Coxsackievirus B-adenovirus receptor, CVB3 binding protein, CVB3-binding protein, HCAR
计算分子量 365 aa, 40 kDa
观测分子量45-55 kDa
GenBank蛋白编号BC003684
基因名称 CXADR
Gene ID (NCBI) 1525
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP78310
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Coxsackievirus and adenovirus receptor (CXADR) is a member of junctional adhesion molecules, which are glycosylated transmembrane proteins that belong to the Ig superfamily (PMID: 17916321). CXADR plays essential roles in blastocyst formation, including cavitation and the proper subcellular localization of tight junction proteins into the apical edge of the outer blastomeres (PMID: 26729920). It is also involved in the transepithelial migration of leukocytes through adhesive interactions with junctional adhesion molecule-like protein (JAML) (PMID: 15800062).